3
1
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T17258 |
WRG-28
|
Discoidin Domain Receptor (DDR) | Tyrosine Kinase/Adaptors |
WRG-28 是一种选择性的、细胞外作用的DDR2变构抑制剂 (IC50:230 nM)。它通过受体的变构调节特异地抑制受体-配体相互作用。它通过靶向 DDR2 抑制肿瘤侵袭和迁移,基质的肿瘤支持作用,能够抑制肺中的转移性乳腺肿瘤细胞定植。 | |||
T30533 |
BMS-587101
UNII-5V7E4UQL93 |
||
BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis. | |||
T27382 | FR-217840 | ||
FR-217840, a novel matrix metalloproteinase inhibitor, successfully suppresses joint destruction and suggest that FR217840 may have potential as a novel anti-rheumatic drug. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5S1895 |
Norisoboldine
Laurelliptine,去甲异波尔定,(+)-Laurelliptine |
MAPK; Adenosine Receptor | GPCR/G Protein; MAPK; Neuroscience |
Norisoboldine ((+)-Laurelliptine) 是一种可口服的芳基烃受体激动剂,是乌药中主要的异喹啉类生物碱,可用于类风湿性关节炎和溃疡性结肠炎的研究。 |